Search results for "design [semiconductor detector]"
showing 10 items of 613 documents
A Novel Series of Acylhydrazones as Potential Anti-Candida Agents: Design, Synthesis, Biological Evaluation and In Silico Studies
2019
In the context of an increased incidence of invasive fungal diseases, there is an imperative need of new antifungal drugs with improved activity and safety profiles. A novel series of acylhydrazones bearing a 1,4-phenylene-bisthiazole scaffold was designed based on an analysis of structures known to possess anti-Candida activity obtained from a literature review. Nine final compounds were synthesized and evaluated in vitro for their inhibitory activity against various strains of Candida spp. The anti-Candida activity assay revealed that some of the new compounds are as active as fluconazole against most of the tested strains. A molecular docking study was conducted in order to evaluate the …
Mediterranean Great Conversation
2015
The exit from the Mediterranean emergency requires rethinking its identity in a new perspective. This means recognizing its legitimate role as a “Great Sea in Between”, as a cultural interface able to connect all the citizens that address to it, in everyday life and as individuals, involving them in a real “great conversation” based on the design disciplines. Design, Brand, Visual Identity, Packaging, Social Media, Fashion, Food, Architecture, Music may be powerful antidotes to the immobility of those who mourn a lost Mediterranean harmony and also a viable alternative to the ethnic closure led by the proponents of the Clash of Civilizations.
On the impact of safety requirements, energy prices and investment costs in street lighting refurbishment design
2018
Abstract Street lighting is an indispensable feature for the night landscape of cities. It is important for road safety, users visual comfort, crime prevention and to augment the perceived personal safety. Realize and maintain an adequate street lighting service is very expensive for municipalities with significant impact on their budgets. For this reason, special attention should be paid to the design of new street lighting systems and to the refurbishment of existing ones, since many of them are inadequate. In light of this it is very important to implement street lighting designs that fulfil lighting requirements avoiding energy waste and light pollution and, at the same time, result eco…
The Studio: Reflections and Issues Arising
1999
An advanced Telematic Studio was built at the University of Jyvaskyla to combine the latest technologies for local and distributed work and/or meetings. The objectives were to combine leading edge technologies with ethnographic design principles derived from CSCW and HCI to support a broad range of activities. We informed the design by studies of similar facilities on other sites. The Studio is popular, and it is easy to give glowing accounts of its use. Nevertheless, over three years a significant number of problems have arisen with both technologies and uses. Some of these are local. Others may be generalisable to any ‘cooperative building’. For example: problems with videoconferencing; i…
An ontology for cognitive mimetics
2018
AI and autonomous systems are intended to replace people in several jobs. People have worked in these jobs being able to execute the required information processing. This implies that new technical artefacts must be able to perform equitably effective information processing. Thus, it makes sense to develop the analysis of human information processing in designing intelligent systems. This approach has been termed cognitive mimetics. This paper studies how it would be practical to gain knowledge about human information processing and organize this knowledge using ontologies.
Questions in Cognitive Mimetics
2021
Human thinking advances through questions and answers. Any field of human endeavor is permeated by the presence of questions, answers and presuppositions. Questions have a kind of universality, whereby one can place the question marks on anything, including questions themselves. The process of asking the right questions about the right things and in the right way are key for the explication of an approach. Recently, we have begun thinking about an approach to the design of intelligent technology: Cognitive mimetics. In brief, the idea is to take inspiration of empirical human thinking in specific contexts to develop AI solutions. The purpose of this article is to question this approach from…
Differential Leakage Factor in Electrical Machines Equipped with Asymmetrical Multiphase Windings: a General Investigation
2019
This paper presents an investigation in terms of degree of unbalance and leakage factor of electrical machines equipped with multiphase windings. The analysis has been carried out through 4800 combinations between slots/poles/phases/layers, analyzing the variability of the leakage factor for each condition and determining the optimal region for its minimization. The obtained results demonstrate that the leakage factor could be considerably reduced with the adoption of slightly asymmetrical windings, which represent a favorable option during the early design stage of electrical machines.
REDESIGN OF AN AUTO-LEVELLING BASE FOR SUBMARINE SEISMIC SENSOR
2011
The OBS (acronym of Ocean Bottom Seismometer) is a system to monitor the submarine seismic activity. To properly work, an OBS system needs a suitable auto-levelling base to maintain a fixed (horizontal) position during the measurement phases. In this work a new auto-levelling base for submarine seismic sensors has been designed. During the redesign process a preliminary phase of analysis of the state of art has been made. Afterwards, the technological solutions chosen by different manufactures have been critically analysed, and a full description of their functionalities, working principles and system performances has been carried out. Later, some innovative concepts have been proposed. Amo…
Beyond Clicks and Beeps: In Pursuit of an Effective Sound Design Methodology
2007
Designing effective non-speech audio elements for a user-interface is a challenging task due to the complex nature of sounds and the changing contexts of non-visual interfaces. In this paper we present a design method, which is intended to take into account the complexity of audio design as well as the existing audio environment and the functional context of use. Central to this method is a rich use scenario, presented in the form of a radio play, which is used as a basis for the work of design panels. A previous version of the design method is analysed and specific practical issues are identified. Solutions to these issues are presented in the form of a modified version of the method. In t…
Verso una dimensione narrativa delle mappe
2021
Tra il pensiero e la costruzione dell’architettura il disegno ha un ruolo baricentrico per connettere i diversi protagonisti di una realizzazione e per coinvolgere la collettività facendo percepire inedite prospettive. La scrittura si rivela utile per esplicitare ciò che nella grafica è sotteso e per stabilire un ordine nuovo nel ragionamento progettuale. I rapporti fra segni e significati si moltiplicano nei sistemi informativi recenti in cui si ha la sensazione di poter dire moltissimo (dati numerici e spaziali) ma a volte sfugge quella sintesi indispensabile per una interpretazione concreta, finalizzata alla costruzione di possibili esperienze fisiche. Per l’esplorazione dell’uso di dive…